CBD Anti-inflammatory and Stress Relieving

CBD Molecular FormulaBoth CBD and THC share the exact same molecular formula, C21H30O2, containing twenty-one atoms of carbon, thirty of hydrogen and two of oxygen.


The culture around cannabis has become more sophisticated and interest is burgeoning in the health science field around its use, specifically the second most common cannabinoid compound, cannabidiol or CBD. Cannabidiol has percolated into the health and research field in terms of its potential to ameliorate seizure activities in some types of epilepsy, to quell symptoms for those with anxiety and psychiatric disorders, to mitigate inflammation and even help alleviate chronic pain.

What is CBD?

Cannabidiol is a cannabinoid extracted from the flowers and leaves of the Cannabis sativus plant and dissolved into an edible carrier oil. Unlike the other most common cannabinoid called tetrahydrocannabinol or THC, CBD does not produce the characteristic “high”, or psychoactive properties that are commonly associated with cannabis consumption or smoke inhalation of burning the leaves/flowers of the plant (Burstein, 2015).

Physiological effects and endocannabinoid system

ECS

The central nervous system of us humans, contains an endocannabinoid system (ECS), where we have receptors for endogenous cannabinoids that bind to them and produce a plethora of effects to maintain homeostasis such as memory, immune function, appetite and metabolism, sleep and mood among other things. The phytocannabinoid CBD found in cannabis, seems to have a complex role in activating and antagonizing the ECS system that is unlike that of THC, which directly binds to those receptors and elicits the intoxicating and rewarding effects (Burstein, 2015).

Emotion

Cannabidiol also seems to bind to certain serotonin receptors in brain regions such as the amygdala that are implicated in emotional processing, fear and anxiety. To bolster these anti-anxiety effects, CBD also increases the amount of our own endocannabinoid compounds (endogenous cannabinoids) within the brain as well. Therefore, CBD shows promise as an anxiolytic and reduces feelings of fear, anxiety and depression, and may help people afflicted with depressive and psychiatric disorders (Campos, Fogaça, Sonego, & Guimarães, 2016) & (Zlebnik & Cheer, 2016).

Cannabis Plan, CBD Oil Variety, CBD Oil VesselCBD has manifested in various forms. As the build-up of CBD surges, buyers are discovering varied methods of consumption. The most prevalent practice of CBD products embrace oils, essences, make-up, topicals, ingestibles, concentrates and drinks.

 

Epilepsy

Moreover, cannabidiol appears to help those with certain types of epilepsy through the activation of inhibitory neurons and neurotransmitters that help “calm” excitatory neurotransmission, which in effect, reduces seizure activity (Grinspoon, P., 2020).

Inflammation

In terms of inflammation, CBD seems to acts as an antioxidant and increases the genetic expression of certain parts of the antioxidant systems in the body that help to promote the scavenging of reactive oxygen species that promote cell damage and inflammation. In addition, it also helps to prevent inflammation, oxidative stress and neuronal death in the brain by preventing plaque development and by suppressing compounds in the body that promote inflammation. This central nervous system protection has promise to help those with neurodegenerative disorders and even as an anti-tumorigenic (cancer) pharmaceutical (Zlebnik & Cheer, 2016) & (Campos, Fogaça, Sonego, & Guimarães, 2016).

Synopsis

The original notion of marijuana’s use is an archaic one and gone are the days where cannabis consumption was viewed under the amusing parody of Cheech and Chong’s “Up in smoke”, where people would languidly sit and laugh while immersed in a cloud of marijuana smoke. Cannabis consumption has largely lost that notoriety and has been legalized across Canada for legal-aged users, and in some states in the USA.

CBD products seem to hold much promise in helping people reduce inflammation, anxiety and depression and even appear to be neuroprotective and may help people manage certain neurodegenerative disorders.  With rise of legalization and social acceptance, industrialists have realized the true benefits of this extract and its ease of use in various applications.  From creams to drinks, all natural CBD is on its way to become a mainstream application rivaling giants in the pain relief and body comfort space.  Imagine, pain relief without the side effects of Tylenol or Advil that commonly cause liver damage or ulcers; a result from the use of ibuprofen or acetaminophen.


Tonic, Turmeric Anti-inflammatory Tea

References

Burstein, S. (2015). Cannabidiol (CBD) and its analogs: a review of their effects on inflammation. Bioorganic & Medicinal Chemistry23(7), 1377–1385. doi: 10.1016/j.bmc.2015.01.059

Campos, A. C., Fogaça, M. V., Sonego, A. B., & Guimarães, F. S. (2016). Cannabidiol, neuroprotection and neuropsychiatric disorders. Pharmacological Research112, 119–127. doi: 10.1016/j.phrs.2016.01.033

Zlebnik, N. E., & Cheer, J. F. (2016, July 8). Beyond the CB1 Receptor: Is Cannabidiol the Answer for Disorders of Motivation? Retrieved from:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818147/

Grinspoon, P. (2020, April 22). Cannabidiol (CBD) - What we know and what we don't. Retrieved from:
https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476

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